Concentration-independent spontaneously forming biomimetric vesicles.

نویسندگان

  • M-P Nieh
  • T A Harroun
  • V A Raghunathan
  • C J Glinka
  • J Katsaras
چکیده

In this Letter we present small-angle neutron scattering data from a biomimetic system composed of the phospholipids dimyristoyl and dihexanoyl phosphorylcholine (DMPC and DHPC, respectively). Doping DMPC-DHPC multilamellar vesicles with either the negatively charged lipid dimyristoyl phosphorylglycerol (DMPG, net charge -1) or the divalent cation, calcium (Ca2+), leads to the spontaneous formation of energetically stabilized monodisperse unilamellar vesicles whose radii are concentration independent and in contrast with previous experimental observations.

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عنوان ژورنال:
  • Physical review letters

دوره 91 15  شماره 

صفحات  -

تاریخ انتشار 2003